Have you made a bus line in editor?
If not, click on Tracks&routes tab, i think it's called something like that.
Then one by one assign parts of splines where the bus route will be.
After you get direction A and direction B then add bus stops to their spline parts along the way.
Then in the same tab click on Edit profiles, make new named standard, you can either edit your own times between bus stops or leave assigned ones.
Close that window and in same tab click Edit timetable, create a new line, create a new tour named whatever you like, and edit starting times using profiles you created before.
Hope this helps you.